Drug Metabolism Panels
Technologies: Pyromark MD Pyrosequencer (Biotage / Qiagen) , ABI 3730xl DNA Analyzer
Applications: SNP panel , Individual SNP Alleles, Custom Design Metabolism Panels.
With the increasing requirement by FDA for drug metabolism studies, Ambry Genetics is well positioned to meet your needs. We offer a choice of drug metabolism studies that can be customized according to your specific project requirements. Our team is here to help you reach your project goals.
Drug Metabolism Panels Available:
CYP2D6 mutations can affect metabolism of drugs including but not limited to tricyclic antidepressants, SSRIs, antipsychotics, antiarrythmics, beta-blockers, opioid analgesics, antiemetics, and antihistamines.
CYP2C9 mutations can affect metabolism of drugs including but not limited to coumarin, anticoagulants, sulfonylureas, angiotensin II receptor blockers, NSAIDs, and phenytoin.
CYP2C19 mutations can affect metabolism of drugs including but not limited to antifungals, proton pump inhibitors, benzodiazepines and antivirals.
CYP3A5 mutations can affect metabolism of drugs including but not limited to macrolide antibiotics, benzodiazepines, antivirals, antihistamines and calcium channel blockers.
VK0RC1 mutations reduce the amount of VK0RC1 protein produced, affecting the dosing amount of the anti-coagulant drug Warfarin.
DMET™ (Drug-Metabolizing Enzymes and Transporters) panel consists of 1,936 markers in all FDA-validated genes and covers more than 90 percent of the current ADME Core markers as defined by the Pharma ADME group.
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Agilent Certified Solutions Provider.
We are proud to be an
Illumina Certified Service Provider.
Ambry Genetics utilizes
RainDance Technologies.
Established as an Agilent SureSelect© Certified Provider.
